Research Scientist (Metabolomics)

Company: The University Of Chicago
Location: Chicago
Posted on: November 16, 2024

Job Description:

Research Scientist (Metabolomics) page is loaded Research Scientist (Metabolomics) Apply locations Chicago, IL time type Full time posted on Posted 30+ Days Ago job requisition id JR27646 Department
-BSD CCC - Metabolomics Platform
About the Department
-The University of Chicago Comprehensive Cancer Center (UCCCC) is an integral component of the Biological Sciences Division (BSD). The BSD is the largest of four Divisions of the University and includes the Pritzker School of Medicine. UCCCC administers four established scientific programs, and the NCI-sponsored Cancer Center Support Grant provides funding for ten Shared Resources. The Comprehensive Cancer Center is comprised of over 190 faculty members from twenty departments with members currently being awarded over $47 million in total direct costs in peer-reviewed cancer research grants, and $28 million in non-peer reviewed grants and contracts. The activities of the Center are broad and varied, including research, training and education, communications, fundraising, marketing, clinical trials management and community outreach.

UCCCC has one of the largest cancer clinical trials programs in the country and in the Chicago area with nearly 500 adult and pediatric therapeutic trials actively accruing patients. Many of these studies are investigator-initiated, including Phase I or I/II trials, demonstrating UCCCC commitment to translate basic research findings to the clinic through proof-of-principle and early phase studies. UCCCC opens over 250 new trials each year and accrues approximately 900 participants to therapeutic trials each year
Job Summary
-Recently UCCCC has created a new metabolomics platform and it is part of a new BSD multi-omics facility. The Metabolomics Platform's mission is to provide both: (1) cutting-edge metabolomics services and (2) expertise in metabolomics research development and experimental design to researchers in the Division, the University, and the Chicago area. We are seeking a research scientist to aid in the facility's advancement, establish metabolite profiling methods using state-of-the-art liquid chromatography-mass spectrometry systems, and perform routine metabolite sample preparation and analysis. Over time, research scientist will become experts in metabolite extraction from a wide variety of sample matrices, liquid chromatography-mass spectrometry (LC-MS) method development and troubleshooting, quantitative analysis of metabolites, stable isotope tracing, and metabolomics data analysis.

We seek a Metabolomics -Research Scientist for the University of Chicago Comprehensive Cancer Center Metabolomics platform. This individual would directly report to the Metabolomics Platform Director and will have ample opportunity to grow and become an expert in metabolomics.

The job performs routine assignments that facilitate and promote a research project or contributes to the scientific direction of a research resource. Receives instruction, guidance, and direction from others.Responsibilities

• Extracts metabolites from samples( cell culture, murine tissues, human biopsy and biofluids etc) and quantify concentration using LC-MS.
• Analyzes mass spec/metabolomics data using specialized software programs (Tracefinder, Compound Discoverer, Skyline etc.).
• Documents sample preparation, method development notes and data analysis results for the publication and reports.
• Prepares mobile phases, stock solutions, troubleshoot process failures and participate in optimization of protocols.
• Maintains inventory of lab supplies.
• Interacts with students and other laboratory staff under the direction of the metabolomics platform director.
• Aids the metabolomics platform director in advancing the technologies and managing day-to-day workflow.
• Analyzes and maintains data and/or specimens.
• Conducts literature reviews.
• Participates in the preparation and writing of grant applications and reports, and co-authors/authors scientific research manuscripts. Provides peer review of grant applications and scientific manuscripts.
• Collaborates on development of new research projects with academic and community-based organizations.
• May present work at scientific meetings.
• Performs other related work as needed.
  Minimum Qualifications
  -Education:Minimum requirements include a PhD in related field.---
  Work Experience:Minimum requirements include knowledge and skills developed through ---
  Certifications:---Preferred QualificationsEducation:
  • PhD in chemistry, analytical chemistry, biochemistry, chemical engineering or related field.Experience:
    • Hands on experience with basic chromatography and mass spectrometry techniques (GC-MS or LC-MS, LC-MS/MS) for small molecule analysis.
    • Experience working in a research laboratory or core facility.
    • Prior experience working with Thermo LC-MS instrument is a plus, but not required.
    • Proficiency in the use of computers and related software programs.Working Conditions
      • Ability to bend, crouch, or stoop.
      • Ability to lift loads up tp 49lbs.Application Documents
        • Resume (required)
        • Cover letter (preferred)
          When applying, the document(s) MUST -be uploaded via the My Experience page, in the section titled Application Documents of the application.
          Job Family
          -Research
          Role Impact
          -Individual Contributor
          FLSA Status
          -Exempt
          Pay Frequency
          -Monthly
          Scheduled Weekly Hours
          -40
          Benefits Eligible
          -Yes
          Drug Test Required
          -No
          Health Screen Required
          -Yes
          Motor Vehicle Record Inquiry Required
          -No
          Posting Statement
          - The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, national or ethnic origin, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination. Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form. We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange. All offers of employment are contingent upon a background check that includes a review of conviction history.A conviction does not automatically preclude University employment.Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position. The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: - http://securityreport.uchicago.edu . -Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637. Similar Jobs (5) Research Scientist, Metabolomics locations Chicago, IL time type Full time posted on Posted 7 Days Ago Research Scientist locations Chicago, IL time type Full time posted on Posted 17 Days Ago Research Professional, Analyst locations Chicago, IL time type Full time posted on Posted 30+ Days Ago
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Keywords: The University Of Chicago, Evanston , Research Scientist (Metabolomics), Other , Chicago, Illinois